解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Indole alkaloids, oxytrofalcatins A-F (1-6), together with five other known alkaloids (7-11), were isolated from the roots of Oxytropis falcata. Their structures were elucidated by comprehensive spectroscopic analyses, including using 1D and 2D NMR spectroscopy and mass spectrometry. This is the first report of N-benz...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2010.02.010
更新日期:2010-06-01 00:00:00
abstract::One of the most well-characterised plant pathogenic interactions involves Arabidopsis thaliana and the bacteria Pseudomonas syringae pathovar tomato (Pst). The standard Pst inoculation procedure involves infiltration of large populations of bacteria into plant leaves which means that metabolite changes cannot be readi...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2010.01.006
更新日期:2010-04-01 00:00:00
abstract::Among the four cold shock domain proteins (CSDPs) identified in Arabidopsis thaliana, it has recently been shown that CSDP1 harboring seven CCHC-type zinc fingers, but not CSDP2 harboring two CCHC-type zinc fingers, function as a RNA chaperone during cold adaptation. However, the structural features relevant to this d...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.12.006
更新日期:2010-04-01 00:00:00
abstract::Herbivory and wounding upregulate a large suite of defense genes in hybrid poplar leaves. A strongly wound- and herbivore-induced gene with high similarity to Arabidopsis vegetative storage proteins (VSPs) and acid phosphatase (AP) was identified among genes strongly expressed during the poplar herbivore defense respo...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2010.01.001
更新日期:2010-04-01 00:00:00
abstract::Fractionation of an ethanol extract of a Madagascar collection of the leaves and fruit of Cassipourea lanceolata Tul. led to the isolation of three euphane triterpenoids 1-3. The (1)H and (13)C NMR spectra of all compounds were fully assigned using a combination of 2D NMR experiments, including COSY, TOCSY, HSQC (HMQC...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.12.009
更新日期:2010-04-01 00:00:00
abstract::Three plant proteinase inhibitors BbKI (kallikrein inhibitor) and BbCI (cruzipain inhibitor) from Bauhinia bauhinioides, and a BrTI (trypsin inhibitor) from B. rufa, were examined for other effects in Callosobruchus maculatus development; of these only BrTI affected bruchid emergence. BrTI and BbKI share 81% identitie...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.10.009
更新日期:2010-02-01 00:00:00
abstract::In plants, it has been proposed that hexacoordinate (class 1) non-symbiotic Hbs (nsHb-1) function in vivo as peroxidases. However, little is known about peroxidase activity of nsHb-1. We evaluated the peroxidase activity of rice recombinant Hb1 (a nsHb-1) by using the guaiacol/H2O2 system at pH 6.0 and compared it to ...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.09.016
更新日期:2010-01-01 00:00:00
abstract::The genome of Brachypodium distachyon, also known as purple false brome, was fully sequenced in 2008 largely in response to the demand for a model plant for temperate grasses. A comparative study of the primary cell walls of seedlings of B. distachyon, Hordeum vulgare and Triticum aestivum was carried out. The cell wa...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.09.019
更新日期:2010-01-01 00:00:00
abstract::The ginseng pathogen Pythium irregulare is able to selectively metabolize the 20(S) protopanaxadiol ginsenosides Rb1, Rb2, Rc, Rd, and gypenoside XVII via extracellular glycosidases, leading to the formation and partial assimilation of ginsenoside F2. Herein we have partially purified three ginsenoside-deglycosylating...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.09.007
更新日期:2009-12-01 00:00:00
abstract::The multitude of terpene carbon skeletons in plants is formed by enzymes known as terpene synthases. This review covers the monoterpene and sesquiterpene synthases presenting an up-to-date list of enzymes reported and evidence for their ability to form multiple products. The reaction mechanisms of these enzyme classes...
journal_title:Phytochemistry
pub_type: 杂志文章,评审
doi:10.1016/j.phytochem.2009.07.030
更新日期:2009-10-01 00:00:00
abstract::Acylation is a prevalent chemical modification that to a significant extent accounts for the tremendous diversity of plant metabolites. To catalyze acyl transfer reactions, higher plants have evolved acyltransferases that accept beta-acetal esters, typically 1-O-glucose esters, as an alternative to the ubiquitously oc...
journal_title:Phytochemistry
pub_type: 杂志文章,评审
doi:10.1016/j.phytochem.2009.07.023
更新日期:2009-10-01 00:00:00
abstract::Marine sponges are an unusually rich source of bioactive natural products with clinical potential. They also often harbor rich communities of symbiotic bacteria that have often been suspected as the true producers of sponge-derived compounds. To date, these bacteria can in most cases not be cultivated, but culture-ind...
journal_title:Phytochemistry
pub_type: 杂志文章,评审
doi:10.1016/j.phytochem.2009.04.010
更新日期:2009-10-01 00:00:00
abstract::Recognition between mating partners, early sexual morphogenesis and development are regulated by a family of beta-carotene derived signal compounds, the trisporoids, in zygomycete fungi. Mating type-specific precursors are released from the hyphae and exert their physiological effects upon compatible mating partners. ...
journal_title:Phytochemistry
pub_type: 杂志文章,评审
doi:10.1016/j.phytochem.2009.07.014
更新日期:2009-10-01 00:00:00
abstract::Aromatic prenyltransferases transfer prenyl moieties onto aromatic acceptor molecules, catalyzing an electrophilic substitution of the aromatic ring under formation of carbon-carbon bonds. They give rise to an astounding diversity of primary and secondary metabolites in plants, fungi and bacteria. This review describe...
journal_title:Phytochemistry
pub_type: 杂志文章,评审
doi:10.1016/j.phytochem.2009.05.009
更新日期:2009-10-01 00:00:00
abstract::Benzoxazinoids are secondary metabolites that are effective in defence and allelopathy. They are synthesised in two subfamilies of the Poaceae and sporadically found in single species of the dicots. The biosynthesis is fully elucidated in maize; here the genes encoding the enzymes of the pathway are in physical proxim...
journal_title:Phytochemistry
pub_type: 杂志文章,评审
doi:10.1016/j.phytochem.2009.05.012
更新日期:2009-10-01 00:00:00
abstract::Putrescine N-methyltransferase (PMT) catalyses S-adenosylmethionine (SAM) dependent methylation of the diamine putrescine. The product N-methylputrescine is the first specific metabolite on the route to nicotine, tropane, and nortropane alkaloids. PMT cDNA sequences were cloned from tobacco species and other Solanacea...
journal_title:Phytochemistry
pub_type: 杂志文章,评审
doi:10.1016/j.phytochem.2009.06.012
更新日期:2009-10-01 00:00:00
abstract::Beneficial soil-borne microorganisms can induce an enhanced defensive capacity in above-ground plant parts that provides protection against a broad spectrum of microbial pathogens and even insect herbivores. The phytohormones jasmonic acid (JA) and ethylene emerged as important regulators of this induced systemic resi...
journal_title:Phytochemistry
pub_type: 杂志文章,评审
doi:10.1016/j.phytochem.2009.06.009
更新日期:2009-09-01 00:00:00
abstract::Lipid oxidation is a common metabolic reaction in all biological systems, appearing in developmentally regulated processes and as response to abiotic and biotic stresses. Products derived from lipid oxidation processes are collectively named oxylipins. Initial lipid oxidation may either occur by chemical reactions or ...
journal_title:Phytochemistry
pub_type: 杂志文章,评审
doi:10.1016/j.phytochem.2009.05.008
更新日期:2009-09-01 00:00:00
abstract::Glucosylation is a predominant flavonoid modification reaction affecting the solubility, stability, and subsequent bioavailability of these metabolites. Flavonoid glycosides affect taste characteristics in citrus making the associated glucosyltransferases particularly interesting targets for biotechnology applications...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.07.027
更新日期:2009-07-01 00:00:00
abstract::Glucosinolates are sulphur-containing glycosides found in brassicaceous plants that can be hydrolysed enzymatically by plant myrosinase or non-enzymatically to form primarily isothiocyanates and/or simple nitriles. From a human health perspective, isothiocyanates are quite important because they are major inducers of ...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.07.035
更新日期:2009-07-01 00:00:00
abstract::Three phenolic glycosides 5-O-{[5''-O-E-(4'''-O-threo-guaiacylglycerol)-feruloyl]-beta-apiofuranosyl-(1-->2)-beta-xylopyranosyl} gentisic acid, 5-O-[(5''-O-vanilloyl)-beta-apiofuranosyl-(1-->2)-beta-xylopyranosyl] gentisic acid and 1-O-[E-(4'''-O-threo-guaiacylglycerol)-feruloyl]-3-O-beta-galacturonopyranosyl glycerol...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.07.021
更新日期:2009-07-01 00:00:00
abstract::The methanolic extract from the pericarps of Sapindus rarak DC. was found to show pancreatic lipase inhibitory activity (IC50=ca. 614 microg/mL). From the extract, oleanane-type triterpene oligoglycosides, rarasaponins I-III (1-3), and raraoside A (4), were isolated together with 13 known saponins and four known sesqu...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.06.015
更新日期:2009-06-01 00:00:00
abstract::Four tetracyclic oxindole alkaloids, 7(R)- and 7(S)-geissoschizol oxindole (1 and 2), 7(R),16(R)- and 7(S),16(R)-19(E)-isositsirikine oxindole (3 and 4), in addition to a taberpsychine derivative, N(4)-demethyltaberpsychine (5), were isolated from the Malayan Tabernaemontana corymbosa and the structures were establish...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.06.010
更新日期:2009-06-01 00:00:00
abstract::Cistus creticus L., an aromatic species from the Mediterranean area, contains various diterpenes bearing the labdane skeleton. The production of essential oil from this species has potential economic value, but so far, it has not been optimized. In order to contribute to a better knowledge of this species and to its d...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.06.013
更新日期:2009-06-01 00:00:00
abstract::The mulberry (Morus spp.)-silkworm (Bombyx mori) relationship has been a well-known plant-herbivore interaction for thousands of years. Recently, we found that mulberry leaves defend against insect herbivory by latex ingredients. Here we report that a 56-kDa (394 amino acid) defense protein in mulberry latex designate...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.04.014
更新日期:2009-05-01 00:00:00
abstract::The dicarboxylic acid malate has long been thought to play important roles in plant physiology. In addition to being a major photosynthate in C4 and CAM plants and an intermediate of the tricarboxylic acid cycle it has been proposed to play essential roles in pH regulation and important roles in pathogen response, as ...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.04.023
更新日期:2009-05-01 00:00:00
abstract::Plant growth and developmental processes as well as environmental responses require the action and cross talk of phytohormones including auxins and cytokinins. Active phytohormones are changed into multiple forms by acylation, esterification or glycosylation, for example. It seems that conjugated compounds could serve...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.05.006
更新日期:2009-05-01 00:00:00
abstract::A broad-based characterisation of a pharmacologically active dichloromethane extract from Isatis tinctoria leaves was carried out. For a comprehensive picture we also included the polar constituents of I. tinctoria (MeOH extract) and for comparative purposes, the taxonomically closely related plant I. indigotica. Diod...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.04.019
更新日期:2009-05-01 00:00:00
abstract::Direct hyphenation of analytical-scale high-performance liquid chromatography, photo-diode array detection, mass spectrometry, solid-phase extraction and nuclear magnetic resonance spectroscopy (HPLC-PDA-MS-SPE-NMR) has been used for accelerated dereplication of crude extract of Haplophyllum acutifolium (syn. Haplophy...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.05.004
更新日期:2009-05-01 00:00:00
abstract::Triterpenoid saponins, impatienosides A-G, together with 12 known saponins, were isolated from the whole plants of Impatiens siculifer. Their structures were established on the basis of extensive 1D and 2D NMR and MS analyses coupled with chemical degradation. Cytotoxic activities of the isolated saponins were evaluat...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.03.022
更新日期:2009-04-01 00:00:00
abstract::Leishmanicidal activity of 6alpha, 7alpha, 15beta, 16beta, 24-pentacetoxy-22alpha-carbometoxy-21beta,22beta-epoxy-18beta-hydroxy-27,30-bisnor-3,4-secofriedela-1,20 (29)-dien-3,4 R-olide (LLD-3 (1)) isolated from Lophanthera lactescens Ducke, a member of the Malpighiaceae, was demonstrated against intramacrophage amast...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.03.009
更新日期:2009-03-01 00:00:00
abstract::Papain (EC 3.4.22.2), the archetypal cysteine protease of C1 family, is of considerable commercial significance. In order to obtain substantial quantities of active papain, the DNA coding for propapain, the papain precursor, has been cloned and expressed at a high level in Escherichia coli BL21(DE3) transformed with t...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.02.001
更新日期:2009-03-01 00:00:00
abstract::In order to study the evolution of pathways of plant secondary metabolism, we use the biosynthesis of pyrrolizidine alkaloids (PAs) as a model system. PAs are regarded as part of the plant's constitutive defense against herbivores. Homospermidine synthase (HSS) is the first specific enzyme of PA biosynthesis. The gene...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.01.019
更新日期:2009-03-01 00:00:00
abstract::Phospholipase D (PLD) catalyzes the hydrolysis and transesterification of glycerophospholipids at the terminal phosphodiester bond. In many plants, several isoforms of PLD have been identified without knowing their functional differences. In this paper, the specificities of two PLD isoenzymes from white cabbage (Brass...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.01.011
更新日期:2009-02-01 00:00:00
abstract::Two 1-aminocyclopropane-1-carboxylic acid (ACC) oxidase (ACO) genes have been cloned from RNA isolated from leaf tissue of apple (Malus domestica cv. Royal Gala). The genes, designated MD-ACO2 (with an ORF of 990bp) and MD-ACO3 (966bp) have been compared with a previously cloned gene of apple, MD-ACO1 (with an ORF of ...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2009.01.002
更新日期:2009-02-01 00:00:00
abstract::Terpene synthases (TPS) require divalent metal ion co-factors, typically magnesium, that are bound by a canonical DDXXD motif, as well as a putative second, seemingly less well conserved and understood (N/D)DXX(S/T)XXXE motif. Given the role of the Ser/Thr side chain hydroxyl group in ligating one of the three catalyt...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2008.12.022
更新日期:2009-02-01 00:00:00
abstract::Chemical investigation of the vines and leaves of Momordica charantia resulted in isolation of fourteen cucurbitane triterpenoids, kuguacins F-S (1-14), including two pentanorcucurbitacins (6 and 7), one octanorcucurbitacin (8), and two trinorcucurbitacins (11 and 12), along with six known analogues. Their structures ...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2008.10.011
更新日期:2009-01-01 00:00:00
abstract::A benzil, calophione A, 1-(6'-Hydroxy-1',3'-benzodioxol-5'-yl)-2-(6''-hydroxy-2''-isopropenyl-2'',3''-dihydro-benzofuran-5''-yl)-ethane-1,2-dione and three coumestan derivatives, tephcalostan B, C and D were isolated from the roots of Tephrosia calophylla. Their structures were deduced from spectroscopic data, includi...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2008.10.009
更新日期:2009-01-01 00:00:00
abstract::Cassane diterpenoids: pulcherrin A, pulcherrin B, pulcherrin C, neocaesalpin P, neocaesalpin Q and neocaesalpin R, together with eight known compounds: isovouacapenol C, 6beta-cinnamoyl-7beta-hydroxy-vouacapen-5alpha-ol, pulcherrimin E, pulcherrimin C, alpha-cadinol, 7-hydroxycadalene, teucladiol and bonducellin were ...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2008.12.006
更新日期:2009-01-01 00:00:00
abstract::Abscisic acid (ABA) has been implicated as a mediator in plant responses to various environmental stresses. To evaluate the transcriptional and metabolic events downstream of ABA perception, Arabidopsis thaliana seedlings were analyzed by transcript and metabolite profiling, and results were integrated, using the rece...
journal_title:Phytochemistry
pub_type: 杂志文章
doi:10.1016/j.phytochem.2008.09.020
更新日期:2008-12-01 00:00:00